COMBINATIONS OF ANTIBODIES SELECTIVE FOR A TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND RECEPTOR AND OTHER THERAPEUTIC AGENTS

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专利权人:

UAB RESEARCH FOUNDATION; BIRMINGHAM

发明人:

申请号：

HU0600602

公开号：

HU0600602A3

申请日:

2002.10.25

申请国别(地区):

HU

年份:

2012

代理人:

摘要：

An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth.

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中国工程科技知识中心

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http://www.ckcest.cn/home/