TREATMENT OF CANCER BY INHIBITING EZH2 ACTIVITY

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专利权人:

发明人:

申请号：

EP15823587.9

公开号：

EP3236962A2

申请日:

2015.12.18

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention relates to inhibitors of EZH2 for use in the treatment of cancers characterised by expression of mutated histone H3 having a mutation of amino acid number 27. The invention also relates to methods for predicting the efficacy of treatment of a cancer with an inhibitor of EZH2 by determining whether the cancer cells contain a gene encoding p16INK4A, wherein the presence of a gene encoding p16 INK4A is indicative of efficacy of treatment of the cancer with an inhibitor of EZH2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/