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INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA
专利权人:
发明人:
申请号:
HK16113008.5
公开号:
HK1224674A
申请日:
2016.11.11
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K delta ) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3K delta plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3K delta , while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3K delta activity, including compounds that selectively inhibit PI3K delta activity. Methods of using PI3K delta inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3K delta inhibitory compounds to inhibit PI3K delta-mediated processes in vitro and in vivo.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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