SMAHOVSKY, VENDELIN,MURANYI, ANDREJ,PSENKOVA, JANA,SNAUKO, MARIAN
申请号：
EP11173982.7
公开号：
EP2545940A1
申请日:
2011.07.14
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Es wird die Herstellung einer Formulierung beschrieben, die eine parenterale Verabreichung eines Vitamin-D analogons mit geringeren Gehalten an organischen Lösungsmitteln ermöglicht.Aqueous pharmaceutical composition comprises vitamin D analogue, water and one or more organic solvents, where the sum of organic solvents does not exceed 45 vol./vol.% in a total amount and the amount of ethanol is = 15 vol./vol.%. An independent claim is included for preparing the composition comprising dissolving vitamin D analogue in ethanol and stirring to obtain a clear solution, mixing the obtained solution with propylene glycol and stirring to obtain a clear solution and mixing the obtained clear solution with water and stirring to obtain a clear solution.
