Ian S. Mitchell,Keith L. Spencer,Peter Stengel,Yongxin Han,Nicholas C. Kallan,Mark Munson,Guy P. A. Vigers,James Blake,Anthony Piscopio,John Josey,Scott Miller,Dengming Xiao,Rui Xu,Chang Rao,Bing Wang
申请号:
US12567258
公开号:
US08680114B2
申请日:
2009.09.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula:A-L-CRwhere CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.