DE KOCK, HERMAN AUGUSTINUS,笛赫曼,笛赫曼,JONCKERS, TIM HUGO MARIA,蒋提姆,蔣提姆,BOONANTS, PAUL JOZEF GABRIEL MARIA,布纳兹,布納茲,LAST, STEFAAN JULIEN,拉斯特,拉斯特,DIERYNCK, INGE,狄英格,狄英格,BAUMEISTER, JUDITH EVA,鲍朱帝,鮑朱帝,VANT K
申请号：
TW096122406
公开号：
TWI415851B
申请日:
2007.06.22
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention relates to 2-(substituted-amino)-benzothiazole sulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present 2-(substituted-amino)-benzothiazole sulfonamide compounds and derivatives with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents.本發明係關於2-(經取代-胺基)-苯并噻唑磺醯胺化合物以及衍生物,其作為蛋白酶抑制劑,特別是作為廣效性HIV蛋白酶抑制劑之用途,其製備方法以及包含彼等之醫藥組合物和診斷套組。本發明亦關於本2-(經取代-胺基)-苯并噻唑磺醯胺化合物以及衍生物與另一種抗反轉錄病毒劑之組合。其進一步係關於其在分析中作為參照化合物或作為試劑之用途。
