The Institute of Cancer Research:Royal Cancer Hospital;Cancer Research Technology Limited;Astex Therapeutics Limited
发明人:
Frederickson, Martyn,Woodhead, Steven John,Rees, David Charles,Grimshaw, Kyla Merriom
申请号：
AU2008224657
公开号：
AU2008224657B2
申请日:
2008.03.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The invention provides a composition comprising (S) 2-amino-1-(4-chloro-phenyl)- 1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol, wherein the composition is either substantially free of (R) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H-pyrazol-4-yl)- phenyl]-ethanol or the composition contains a mixture of the (S) and (R) enantiomers in which the (S) enantiomer predominates. Also provided are processes for the preparation of the (S) 2-amino-1-(4-chloro-phenyl)-1-[4-(1H- pyrazol-4-yl)-phenyl]-ethanol, novel process intermediates and methods for making the novel process intermediates.
