Roger A. Sabbadini,Tom Huxford,Jonathan Michael Wojciak
申请号：
US12794668
公开号：
US08401799B2
申请日:
2010.06.04
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods for designing optimized antibodies, including optimized humainized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them.
