Gregory Alan Lazar,John R. Desjarlais,Philip W. Hammond,David F. Carmichael,Bao-Iu Chen,Seung Y. Chu,Sher Bahadur Karki,Lori Kunkel
申请号:
US13163465
公开号:
US20120014943A1
申请日:
2011.06.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.