Goldenberg, David M.,Hansen, Hans J.,Chang, Chien-Hsing
申请号：
AU2016252771
公开号：
AU2016252771A1
申请日:
2016.04.22
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Described herein are compositions and methods of use of anti-Trop-2 antibodies or antigen-binding fragment thereof to isolate, enrich, detect, diagnose and/or characterize circulating tumor cells (CTCs) from patients with a Trop-2 positive cancer. Preferably, the antibody is an RS7, 162-46.2 or MAB650 antibody. The compositions and methods are of use to detect, diagnose and/or treat metastatic Trop-2
