FRIESE-HAMIM MANJA,KRIER MIREILLE,SEENISAMY JEYAPRAKASHNARAYANAN,ZENKE FRANK,HEINRICH TIMO
申请号：
NZ63019613
公开号：
NZ630196A
申请日:
2013.03.21
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein are compounds of the formula (I) where the substituents are as defined herein. The compounds are methionine aminopeptidase inhibitors and can be used for treating tumours. Also disclosed are methods for the synthesis of the compounds of formula I. Specific examples of the compounds include: 1-benzyl-N-(3-chloro-5-fluorobenzyl)-3-hydroxypiperidine-3-carboxamide and (S)-3-((E)-but-2-enoyl)-3-hydroxy-1-phenylpyrrolidin-2-one.
