The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
Irving William Wainer,Weizhong Zhu,Khalid Chakir,Rui-Ping Xiao,Darrell R. Abernethy,Farideh M. Beigi Abhari
申请号：
US14199208
公开号：
US09522871B2
申请日:
2014.03.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.
