THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES
发明人:
申请号:
IL19696509
公开号:
IL196965A
申请日:
2009.02.09
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding &bgr;2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.