A disposable medical device (1) for lift and transfer of patients between ambulance stretchers (B) and/or hospital stretchers by a healthcare professional (W), which device (1) comprises a sheet support structure (2) having a peripheral portion (3) with longitudinal edges (4) and transverse edges (5). The structure (2) extends to such a length as to be able to support the entire body of a patient, has a top surface (6) that is intended to contact the body of the patient and a bottom surface (7) intended to contact a stretcher (B), wherein the peripheral portion (3) has a plurality of openings (12) adapted to define hand grips for one or more healthcare professionals (W). According to a peculiar aspect of the invention, the openings (12) are conveniently arranged along the edges (4, 5) at predetermined distances (d1, d2, d3, d4) from each other, calculated in combination both with the biometric parameters of the patients being transported and the maximum loads acceptable for healthcare professionals (W) having different muscular strengths, and allowed by injury-prevention regulations.