Kim, Dae Kee,Sheen, Yhun Yhong,Jin, Cheng Hua,Park, Chul-Yong,Sreenu, Domalapally,Rao, Kota Sudhakar,Krishnaiah, Maddeboina,Subrahmanyam, Vura Bala
申请号:
HRP20171829
公开号:
HRP20171829T1
申请日:
2017.11.23
申请国别(地区):
HR
年份:
2018
代理人:
摘要:
This invention relates to 2-pyridyl substituted imidazoles (I) which are inhibitors of the transforming growth factor-² (TGF-²) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.