2-pyridyl-substituted imidazoles as therapeutic Alk5 and / or Alk4 inhibitors

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专利权人:

Ewha University-Industry Collaboration Foundation

发明人:

Kim, Dae Kee,Sheen, Yhun Yhong,Jin, Cheng Hua,Park, Chul-Yong,Sreenu, Domalapally,Rao, Kota Sudhakar,Krishnaiah, Maddeboina,Subrahmanyam, Vura Bala

申请号：

DK15157476

公开号：

DK2947081T3

申请日:

2011.06.24

申请国别(地区):

DK

年份:

2017

代理人:

摘要：

This invention relates to 2-pyridyl substituted imidazoles (I) which are inhibitors of the transforming growth factor-² (TGF-²) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/