KIM DEE KEE,SHEEN YHUN YHONG,JIN CHENG HUA,PARK CHUL-YONG,SREENU DOMALAPALLY,RAO KOTA SUDHAKAR,KRISHNAIAH MADDEBOINA,SUBRAHMANYAM VURA BALA
申请号:
ZA201208662
公开号:
ZA201208662B
申请日:
2012.11.19
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
This invention relates to 2-pyridyl substituted imidazoles (I) which are inhibitors of the transforming growth factor-² (TGF-²) type I receptor (ALK5) and/or the activin type I receptor (ALK4), methods for their preparation, and their use in medicine, specifically in the treatment and prevention of a disease state mediated by these receptors.