Claudia L. Lanari,Victoria Wargon,Paola Rojas,Maria May,Gonzalo Sequeira
申请号:
US14363551
公开号:
US20150202261A1
申请日:
2012.12.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides methods, pharmaceutical compositions and kits for treating a subject having a carcinoma that is resistant to an antiprogestin. In particular, the methods comprise increasing the molar amount of progesterone receptor isoform A (PR-A) so that it is greater than that of isoform B (PR-B) and administering a therapeutically effective amount of an antiprogestin to the subject, thereby treating the carcinoma.