Pyrrole-substituted indolone derivative, preparation method therefor, composition comprising the same and use thereof

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专利权人:

SHIJIAZHUANG YILING PHARMACEUTICAL CO.; LTD.

发明人:

HU, LIHONG,ZHAO, SHAOHUA,LIU, PENG,LI, XIANGJUN,AN, JUNYONG,ZHOU, MENGXIA,ZHANG, LILI,YAO, ZIJIAN

申请号：

SG11201606545S

公开号：

SG11201606545SA

申请日:

2015.02.04

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The invention relates to a pyrrole-substituted indolinone derivative and a preparation method thereof, a composition including the derivative, and application of the derivative. The pyrrole-substituted indolinone derivative has a structure as shown in a general formula (I) which is described in the specification. The invention also relates to application of the pyrrole-substituted indolinone derivative in treatment of receptor tyrosine kinase mediated diseases and a pharmaceutical composition containing the derivative and used for treating diseases related to tumors.

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