Lihong Hu,Shaohua Zhao,Peng Liu,Xiangjun Li,Junyong An,Mengxia Zhou,Lili Zhang,Zijian Yao
申请号:
US15117400
公开号:
US09556154B2
申请日:
2015.02.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a pyrrole-substituted indolone derivative, a preparation method therefor, a composition comprising the derivative, and use thereof. The pyrrole-substituted indolone derivative has a structure shown in formula (I) below. The present invention further relates to use of the pyrrole-substituted indolone derivative for treating receptor tyrosine kinase-mediated diseases, and to a pharmaceutical composition comprising compounds having such a structure for treating related diseases such as tumors.