PROCESS FOR THE PREPARATION OF N-[5-(3-DIMETHYLAMINO-ACRYLOYL)-2-FLUORO-PHENYL]-N-METHYL-ACETAMIDE

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专利权人:

发明人:

JUAN SALLARES ROSELL,FRANCISCO MARQUILLAS

申请号：

IN5197/DELNP/2011

公开号：

IN2011DN05197A

申请日:

2011.07.06

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

a) methylation of N-(5-acetyl-2-fluorophenyl)-N-acetamide (IV) with a methyl sulfonate, b) reaction of the resulting compound (VI) with NNDMF-DMA, and c) reaction of the resulting compound (I) with (5-amino-1H-pirazol-4-yl)thiophen-2-yl-methanone (III) in glacial acetic acid. The present invention also relates to new intermediate (VI).

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