CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.);UNIVERSITE NICE SOPHIA ANTIPOLIS;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM (EPST))
发明人:
BENHIDA RACHID,AUBERGER PATRICK,DRIOWYA MOHSINE,PUISSANT ALEXANDRE,ROBERT GUILLAUME,MALNUIT VINCENT
申请号：
ZA201307451
公开号：
ZA201307451B
申请日:
2013.10.07
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described.
