Disclosed is a flexible surgical instrument system with a prepositioned drive input, comprising a flexible continuous body structure (10) and a driving unit (20). The flexible continuous body structure (10) comprises a distal structural body (101), a proximal structural body (102) and a middle connecting body (103). The distal structural body (101) comprises at least one distal structural segment (104, 105). The distal structural segment (104, 105) comprises a distal spacer plate (106), a distal fixed plate (107) and a structural bone (108). The proximal structural body (102) comprises the same number of proximal structural segments (109, 110) as distal structural segments (104, 105). The proximal structural segment (119, 110) comprise a proximal spacer plate (111), a proximal fixed plate (112) and a structural bone (108). The middle connecting body (103) comprises two channel fixing plates (113), and a structural bone guiding channel (114) provided between the two channel fixing plates (113). The driving unit (20) comprises a driving unit fixing plate (201) provided in front of the middle connecting body (103). A plurality of linear motion mechanisms (202) for converting a rotation input from an electric motor into a linear motion output are provided between the driving unit fixing plate (201) and the channel fixing plates (113). Output ends of the linear motion mechanisms (202) are connected to one end of a driving bone (203), the driving bone (203) passes through the proximal spacer plate (111), and the other end of the driving bone is fixedly connected to the proximal fixed plate (112).L'invention concerne un système d'instrument chirurgical flexible avec une entrée d'entraînement prépositionnée, comprenant une structure de corps continu flexible (10) et une unité d'entraînement (20). La structure de corps continu flexible (10) comprend un corps structural distal (101), un corps structural proximal (102) et un corps de liaison intermédiaire (103). Le corps struc