NIHON MEDI-PHYSICS CO., LTD;National University Corporation Hokkaido University
发明人:
申请号：
EP19160258.0
公开号：
EP3536686A1
申请日:
2019.03.01
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
A simple method for producing a clinically applicable radiopharmaceutical composition containing 1-(2,2-dihydroxymethyl-3-[18F]fluoropropyl)-2-nitroimidazole ([18F]DiFA) or a salt thereof as an active ingredient, is provided which includes a synthesis step of obtaining a crude product of [18F]DiFA from a labeling precursor compound for [18F]DiFA； and a purification step of purifying the crude product, in which the purification step includes purifying [18F]DiFA using two or more different types of reverse phase solid phase extraction cartridges.
