METHODE DE PRODUCTION D'UNE COMPOSITION PHARMACEUTIQUE

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专利权人:

NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;NIHON MEDI-PHYSICS CO., LTD.

发明人:

KIRIU, MASATO,NAKAMURA, SOICHI,KUGE, YUJI,ABO, NORIFUMI

申请号：

CA3034905

公开号：

CA3034905A1

申请日:

2019.02.26

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

A simple method for producing a clinically applicableradiopharmaceutical composition containing1-(2,2-dihydroxymethyl-3- [18F]fluoropropyl)-2-nitroimidazole([18F]DiFA) or a salt thereof as an active ingredient, isprovided which includes a synthesis step of obtaining acrude product of [18F]DiFA from a labeling precursorcompound for [18F]DiFA； and a purification step ofpurifying the crude product, in which the purification stepincludes purifying [18F]DiFA using two or more differenttypes of reverse phase solid phase extraction cartridges.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/