BIEMANS, Barbara,GUBA, Wolfgang,JAESCHKE, Georg,LINDEMANN, Lothar,O,HARA, Fionn,RICCI, Antonio,RUEHER, Daniel,VIEIRA, Eric
申请号：
PH12018500106
公开号：
PH12018500106A1
申请日:
2018.01.12
申请国别(地区):
PH
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula I wherein R1 is lower alkyl； R2 is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be in different positions； n is 0, 1 or 2； V/U are independently from each other O or CH2, wherein V and U cannot be simultaneously O； L is a five or six membered heteroaryl group, selected from or to a pharmaceutically acceptable salt or acid addition salt, to a racemic mixture, or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof. The compounds may be used for the treatment of Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.
