Gino Luigi Vairo,Andrew Nash,Eugene Maraskovsky,Nick Wilson,Samantha Busfield,Con Panousis
申请号:
US14617882
公开号:
US09758585B2
申请日:
2015.02.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.