Compositions and methods for targeting type 1 interferon producing cells

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专利权人:

CSL Limited

发明人:

Vairo, Gino Luigi,Nash, Andrew,Maraskovsky, Eugene,Wilson, Nick,Busfield, Samantha

申请号：

AU2011217728

公开号：

AU2011217728B2

申请日:

2011.02.17

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/