Gino Luigi Vairo;Andrew Nash;Nick Wilson;Samantha Busfield;Eugene Maraskovsky
发明人:
Gino Luigi Vairo,Andrew Nash,Eugene Maraskovsky,Nick Wilson,Samantha Busfield
申请号:
US13579886
公开号:
US08535669B2
申请日:
2011.02.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.