Embodiments of the present invention provide a drug cassette having a compact configuration which allows for drugs to be fed out one at a time using a first rotating body and a second rotating body, and also provide a drug packaging device. The following are arranged within a cassette main body of said drug cassette: a cylindrical body that accommodates the drugs； a first rotating body that is disposed on a bottom surface side of the cylindrical body, the first rotating body being rotatable around a first rotating shaft； and a second rotating body that is disposed on an outer periphery of an opening in the cylindrical body, the second rotating body being rotatable around a second rotating shaft. At least one drive unit, disposed in a remaining space within the cassette main body, to rotate and drive the first rotating body and the second rotating body.
