In some embodiments, a knot tying device includes a body that defines a wheel slot and inner passages that lead to the wheel slot and a wheel that fits and can be rotated within the wheel slot, the wheel including openings that can be aligned with the inner passages of the body, wherein one or more strands of material can be fed through the inner passages of the body and the openings of the wheel and the wheel can then be rotated relative to the body to twist the one or more stands.
