A suture instrument includes: a therapeutic insertion section having a suture section for suturing tissue a cylindrical main operation unit a rod section in the main operation unit, for discharging a suture thread and end section members connected to the suture thread a pushers distal end section for pressing the end section member and a guide mechanism for rotating the rod section after linear movement of the pushers distal end section at a position where one of the end section member is fed from a distal end of the suture section, the rod section being rotated in the circumferential direction to a position where the other one of the end section members is fed from the distal end of the suture section, so that each one of the end section members is discharged one after another and so that the end section members can be separated finally.
