INHIBITEURS DE CANAL A POTENTIEL DE RECEPTEUR TRANSITOIRE A BASE D'OXADIAZOLE

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

TERRETT, JACK ALEXANDER,CHEN, HUIFEN,CONSTANTINEAU-FORGET, LEA,LAROUCHE-GAUTHIER, ROBIN,LEPISSIER, LUCE,BEAUMIER, FRANCIS,DERY, MARTIN,GRAND-MAITRE, CHANTAL,STURINO, CLAUDIO,VOLGRAF, MATTHEW,VILLEMURE

申请号：

CA3091486

公开号：

CA3091486A1

申请日:

2019.03.18

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1?, R4? and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

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中国工程科技知识中心

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http://www.ckcest.cn/home/