Jack Alexander Terrett,Huifen Chen,Lea Constantineau-Forget,Robin Larouche-Gauthier,Luce Lépissier,Francis Beaumier,Martin Déry,Chantal Grand-Maître,Claudio Sturino,Matthew Volgraf,Elisia Villemure
申请号：
US16355352
公开号：
US20190284179A1
申请日:
2019.03.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to compounds of formula I:and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
