Oxadiazole transient receptor potential channel inhibitors

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专利权人:

F. Hoffmann-La Roche AG

发明人:

TERRETT, Jack Alexander,CHEN, Huifen,CONSTANTINEAU-FORGET, Lea,LAROUCHE-GAUTHIER, Robin,LÉPISSIER, Luce,BEAUMIER, Francis,DÉRY, Martin,GRAND-MAÎTRE, Chantal,STURINO, Claudio,VOLGRAF, Matthew,VILLEMURE

申请号：

AU2019237992

公开号：

AU2019237992A1

申请日:

2019.03.18

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1?, R4? and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

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中国工程科技知识中心

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