INSTITUTE OF IMMUNOLOGY CO., LTD.;AKITA UNIVERSITY
发明人:
SHIOTA Akira,MIZOROKI Tatsuya,MORITOKI Yuki
申请号:
WO2016JP63356
公开号:
WO2016175285(A1)
申请日:
2016.04.28
申请国别(地区):
世界知识产权组织国际局
年份:
2016
代理人:
摘要:
The purpose of the present invention is to provide a transgenic non-human animal with which it is possible to appropriately evaluate characteristics, pharmacological effects, and safety of molecularly targeted substances or drugs with respect to human-specific molecules, and to provide a manufacturing method therefor. The transgenic non-human animal is subjected to transgenesis by using genes coding for human-specific molecules and genes coding for the human Fcγ receptor family, thus expressing the genes coding for the human-specific molecules and the genes coding for the human Fcγ receptor family.