The present invention relates to a compound of the general formula (1), wherein A represents CH or a nitrogen atom, R represents a hydrogen or halogen atom, or a linear or branched alkyl group having 1 to 6 carbon atoms. R1 is a hydrogen or halogen atom, a linear or branched alkyl group having 1 to 6 carbon atoms, a linear or branched alkoxy group having 1 to 6 carbon atoms, or a mono- or polyhalogenated straight chain having 1 to 6 carbon atoms A chain or branched haloalkyl group, R2 represents a hydrogen or halogen atom, a linear or branched alkyl group having 1 to 6 carbon atoms, a linear or branched alkoxy group having 1 to 6 carbon atoms, or a carbon number of 1 to 4; A mono- or polyhalogenated straight-chain or branched-chain haloalkyl group, wherein R3 is hydrogen or a straight chain having 1 to 6 carbon atoms optionally substituted with a cycloalkyl group having 3 to 6 carbon atoms. Means a branched alkyl group, a mono- or polyhalogenated linear or branched haloalkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, a linear or branched alkanoyl group having 1 to 6 carbon atoms The said compounds and / or their salts and / or geometric isomers and / or stereoisomers and / or diastereomers and / or hydrates and / or solvates and / or homogeneous images. The present invention relates to novel substituted diazepino-indole derivatives of general formula (1), pharmaceutically acceptable salts thereof, pharmaceutical compositions containing the compounds and intermediates thereof, and melanin-concentrating hormone receptor 1 activity. It relates to the treatment or prevention of disorders.本発明は、一般式(1)の化合物であって、【化1】AはCH又は窒素原子を意味し、Rは水素若しくはハロゲン原子又は炭素数1~6の直鎖若しくは分岐鎖アルキル基を意味し、R1は水素若しくはハロゲン原子、炭素数1~6の直鎖若しくは分岐鎖アルキル基、炭素数1~6の直鎖若しくは分岐鎖アルコキシ基又は炭素数1~6のモノ若しくはポリハロゲン化直鎖若しくは分岐鎖ハロアルキル基を意味し、R2は水素若しくはハロゲン原子、炭素数1~6の直鎖若しくは分岐鎖アルキル基、炭素数1~6の直鎖若しくは分岐鎖アルコキシ基又は炭素数1~4のモノ若しくはポリハロゲン化直鎖若しくは分岐鎖ハロアルキル基を意味し、R3は水素、炭素数3~6のシクロアルキル基で任意に置換されていてもよい炭素数1~6の直鎖若しくは分岐鎖アルキル基、炭素数1~6の