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6-membered aromatic ring derivatives containing nitrogen and pharmaceutical products containing them
专利权人:
Daiichi Sankyo Company; Limited
发明人:
Takemoto, Naohiro,Murata, Kenji,Murayama, Norihito,Yamada, Chikaomi
申请号:
ES13185144
公开号:
ES2566327T3
申请日:
2008.04.25
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A compound represented by the following formula (Ia): ** Formula ** (in which R0 is the group -NR3R4 (in which R3 and R4 are each independently a hydrogen atom, an oxygen atom, an alkyl group not substituted or substituted with straight, branched or cyclic chain halogen having 1 to 5 carbon atoms, or a linear or branched chain alkoxycarbonyl group having 2 to 10 carbon atoms); R1 and R2 are each of form independent of a hydrogen atom, a halogen atom, a hydroxyl group, a straight or branched chain alkoxy group having 1 to 5 carbon atoms, an acetyl group, a carbamoyl group, a carboxyl group, a chain ester group linear or branched having 1 to 5 carbon atoms, a linear, branched or cyclic chain alkyl group not substituted or substituted by halogen having 1 to 5 carbon atoms, or a -NR3R4 group (in which R3 and R4 they are each independently an atom of hid halogen, an oxygen atom, a straight chain, branched or cyclic alkyl group substituted with halogen having 1 to 5 carbon atoms, or a straight or branched chain alkyloxycarbonyl group having 2 to 10 carbon atoms); R5 and R6 are each independently a hydrogen atom or a straight chain, branched or cyclic alkyl group unsubstituted or substituted with halogen having 1 to 5 carbon atoms; R7 is a straight chain, branched or cyclic alkyl group having 1 to 5 carbon atoms; E is an oxygen atom; n is an integer from 0 to 5; X and Y are independently a link connector; a straight or branched chain alkylene group having 1 to 5 carbon atoms, substituted or unsubstituted with 1 to 4 hydroxyl or alkoxy groups; a cycloalkylene group having 3 to 6 carbon atoms, substituted or unsubstituted with 1 to 4 hydroxyl groups, oxygen atoms or alkyl groups; a heterocycloalkylene group, substituted or unsubstituted with 1 to 4 hydroxyl groups, oxygen atoms or alkyl groups; an alkenylene group having 2 to 4 carbon atoms, substituted or unsubstituted with 1 to 4 alkyl groups having 1 to 5 carbon atoms; -NHCO-; -CONH-; -CO-; or -SO2-; and Q is a hydrogen a
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