Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (GIPR) in combination with GLP-1 agonists
Yie, Junming,Shi, Donghui,Lloyd, David J.,Wang, Jinghong,Sivits Jr., Glenn N.,Veniant-Ellison, Murielle M.,Komorowski, Renee,Agrawal, Neeraj,Bates, Darren L.,Clavette, Brandon C. P.,Foltz, Ian N.,Ho,
申请号:
AU2016378739
公开号:
AU2016378739A1
申请日:
2016.12.21
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.