METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS
AGRAWAL, Neeraj,BATES, Darren L.,CLAVETTE, Brandon C. P.,FOLTZ, Ian N.,HO, Shu-yin,KOMOROWSKI, Renee,LLOYD, David J.,MIN, Xiaoshan,MURAWSKY, Christopher,SHI, Donghui,SIVITS, JR.,VENIANT-ELLISON, Murie
申请号:
TN2018000225
公开号:
TN2018000225A1
申请日:
2016.12.21
申请国别(地区):
TN
年份:
2019
代理人:
摘要:
Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.