METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS
YIE, JUNMING,SHI, DONGHUI,LLOYD, DAVID J.,WANG, JINGHONG,SIVITS, GLENN N., JR.,VENIANT-ELLISON, MURIELLE M.,KOMOROWSKI, RENEE,AGRAWAL, NEERAJ,BATES, DARREN L.,CLAVETTE, BRANDON C. P.,FOLTZ, IAN N.,HO,
申请号：
CA3009650
公开号：
CA3009650A1
申请日:
2016.12.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
