A method for the disinfection of climatic cabinets in particular is provided. The method comprises the following steps: generating a disinfecting hot atmosphere in the space to be disinfected by supplying heat and evaporating water in a heating-up phase when a temperature of at least 95±5° C. and a relative humidity of at least 80% are reached at a pressure corresponding substantially to the pressure of the ambient atmosphere, maintaining these process conditions in a disinfection phase for a period of time which is sufficient for killing germs situated in the interior space and subsequently expelling the relative humidity from the space to be disinfected and cooling in a cooling phase, the water vapor generated for disinfection being removed from the space to be disinfected by injecting sterile air in the cooling phase
