PROBLEM TO BE SOLVED: To provide a medicament comprising human Tr1 cells directed to a human heat shock protein (HSP), and methods for treating an inflammatory autoimmune condition.SOLUTION: The invention provides pharmaceutical compositions in which human Tr1 cell populations for treating an inflammatory autoimmune condition are preferably HSP60, HSP70, HSP90 and fragments or mixtures thereof. The invention also provides use of the compositions in combination with one or more effective therapeutic agents. The invention further provides methods of administering 10to 10/kg Tr1 cells to a subject in need thereof.【課題】ヒト熱ショック蛋白質（ＨＳＰ）に向けられるヒトＴｒ１細胞を含有する薬剤、及び炎症性自己免疫病態を治療する方法の提供。【解決手段】炎症性自己免疫病態を治療するためのヒトＴｒ１細胞集団が好ましくはＨＳＰ６０、ＨＳＰ７０、ＨＳＰ９０、およびそれらの断片または混合物である医薬組成物。さらに有効な１つ以上の治療薬と組み合わせる組成物の使用。１０４～１０９／ｋｇのＴｒ１細胞をその必要ある対象に投与する方法。【選択図】なし
