The present invention relates to a process for preparing a crystalline micronised particulate of a glycopyrronium salt. The process involves suspending the drug in a water immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.本發明係有關於製備甘羅溴銨(glycopyrronium)鹽之結晶性微粉化微粒之方法。該方法涉及將該藥物懸浮於水不相溶混之反溶劑內，該藥物於該反溶劑中具有極低或無溶解度，及將該懸浮液予以微粉化。結果所得藥物粒子就儲藏時的附聚及/或聚積而言為物理上安定。
