Hayley Binch;Peter D. J. Grootenhuis;Albert Pierce;Lev T. D. Fanning
发明人:
Hayley Binch,Peter D. J. Grootenhuis,Albert Pierce,Lev T. D. Fanning
申请号:
US12813876
公开号:
US08552006B2
申请日:
2010.06.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds of formula IVA, formula IVB, or formula IVC, useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators.