N-acyl derivatives of amino acids, their preparation, pharmacological compositions and their use as anti-allergic, anti-inflammatory and anti-lipidemic agents

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专利权人:

ネボルシン ウラディミル エフゲニエヴィッチ;レカルストヴァ”;“オテチェストヴェンニェ;オブシェストヴォ;オトクリトエ;オトクリトエ アクツィオネルノエ オブシェストヴォ “オテチェストヴェンニェ レカルストヴァ”;アクツィオネルノエ

发明人:

ネボルシン ウラディミル エフゲニエヴィッチ,クロモヴァ タティアナ アレクサンドロフナ,ゼルツキナ ガリナ アレクサンドロフナ,コヴァレヴァ ヴィオレッタ レオニドフナ

申请号：

JP2013082349

公开号：

JP5836995B2

申请日:

2013.04.10

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention relates to N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof wherein n is 2 or 3； and R 1 represents or pharmaceutically acceptable salts thereof, to novel processes for preparing the same, to use thereof as anti-allergic, anti-anaphylactic, anti-inflammatory and hypolipidemic agents as well as to a pharmaceutical composition comprising the indicated compounds in an efficient amount and to a method for treating allergic and inflammatory diseases and lipid metabolism disorders: bronchial asthma, allergic rhinitis, pollinoses, seasonal and year-round rhinitis, allergic pneumonitis, atopic dermatitis, psoriasis, urticaria, allergic (including anaphylactic) reactions to insect stings and medicaments, cold allergy, allergic conjunctivitis, atherosclerosis, obesity, ischemic heart and cerebral disease, myocardial infarction and stroke.

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