DERIVES N-ACYLES D'ACIDES AMINES, COMPOSITION PHARMACEUTIQUE ET SON UTILISATION EN TANT QUE PRODUITS ANTI-ALLERGIQUES, ANTI-ANAPHYLACTIQUES, ANTI-INFLAMMATOIRES OU HYPOLIPIDEMIQUES
OTKRYTOE AKTSIONERNOE OBSCHESTVO "OTECHESTVENNYE LEKARSTVA";NEBOLSIN, VLADIMIR EVGENIEVICH
发明人:
NEBOLSIN, VLADIMIR EVGENIEVICH,KROMOVA, TATYANA ALEXANDROVNA,ZHELTUKHINA, GALINA ALEXANDROVNA,KOVALEVA, VIOLETTA LEONIDOVNA
申请号：
CA2612324
公开号：
CA2612324C
申请日:
2006.06.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to N-acyl derivatives of amino acids andpharmaceuticallyacceptable salts thereof(see formula I)wherein n is 2 or 3； andR1 represents(see formula II) or (see formula III), R2=H, -CH3, -C2H5or pharmaceutically acceptable salts thereof, to novel processes for preparingthe same, touse thereof as anti-allergic, anti-anaphylactic, anti-inflammatory andhypolipidemic agents aswell as to a pharmaceutical composition comprising the indicated compounds inan efficientamount and to a method for treating allergic and inflammatory diseases andlipid metabolismdisorders: bronchial asthma, allergic rhinitis, pollinoses, seasonal and year-round rhinitis,allergic pneumonitis, atopic dermatitis, psoriasis, urticaria, allergic(including anaphylactic)reactions to insect stings and medicaments, cold allergy, allergicconjunctivitis, atherosclerosis,obesity, ischemic heart and cerebral disease, myocardial infarction andstroke.
