Colorado State University Research Foundation;The Regents of the University of Colorado
发明人:
DOW, Steven,LAPPIN, Michael,WHEAT, William,CHOW, Lyndah,REGAN, Daniel,ANCHORDOQUY, Thomas
申请号：
EP17776850
公开号：
EP3435981A4
申请日:
2017.03.31
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes； a mixture of toll like receptor 3 (TLR3) and toll like receptor 9 (TLR9) ligands； and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal surfaces. In further aspects, disclosed compositions are administered to a mammal in conjunction with an antigen to enhance the immune response of the mammal to the antigen.
