Ronald M. Evans,Michael Downes,Mara Sherman,Ning Ding
申请号:
US15226052
公开号:
US20160331760A1
申请日:
2016.08.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides compositions that include a nanoparticle and a compound that reduces the biological activity of one or more bromodomain and extra-terminal family member (BET) proteins (e.g., a bromodomain inhibitor), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell.