EVANS, RONALD M.,DOWNES, MICHAEL,SHERMAN, MARA,DING, NING
申请号:
CA2938742
公开号:
CA2938742A1
申请日:
2015.02.10
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure provides compositions that include a nanoparticle and a compound that reduces the biological activity of one or more bromodomain and extra-terminal family member (BET) proteins (e.g., a bromodomain inhibitor), and methods of using such compounds to increase retention or storage of vitamin A, vitamin D, and/or lipids by a cell, such as an epithelial or stellate cell.